pydeseq2.dispersions.fit_moments_dispersions#

fit_moments_dispersions(normed_counts, size_factors)#

Dispersion estimates based on moments, as per the R code.

Used as initial estimates in DeseqDataSet.fit_genewise_dispersions().

Parameters:

normed_counts ndarray: Array of deseq2-normalized read counts. Rows: samples, columns: genes.
size_factors ndarray: DESeq2 normalization factors.

Return type:

Returns:

Estimated dispersion parameter for each gene.